Mead will star as the title character while Pasquale will play his hapless brother, Wishee Washee.
Comedian and actor Mead is one of the UK's best known comics and has spent more than 20 years on both the screen and stage. He's been in the I'm A Celebrity jungle, taken part in no fewer than five The Royal Variety Performances and starred in the West End production of Spamalot.
Mead rose to fame when he won BBC talent show Any Dream Will Do, securing he lead role in Andrew Lloyd-Webber’s Joseph and the Amazing Technicolor Dreamcoat. He's gone on to appear in Legally Blonde on the stage and Holby City on screen.
This will be his sixth panto, with previous starring roles including Prince Charming in Cinderella at the London Palladium.
Aladdin will play at the Milton Keynes Theatre between Saturday, 7th December and Sunday, 12 January.
Emma Sullivan, Theatre Director at Milton Keynes Theatre said: “We’re thrilled to welcome the return of Qdos Entertainment to Milton Keynes Theatre following the roaring success of Robin Hood last year.
"We’re looking forward to having Lee Mead in MK this Christmas, he’s a firm audience favourite and we know he’ll go down a storm as Aladdin.”
The official Milton Keynes Theatre twitter posted: "We are THRILLED to announce our panto stars, @itreallyisjoe and @leemeadofficial! Joe and Lee will be starring in our 2019 - 2020 panto 🧞 Aladdin 🧞 from Sat 7th Dec to Sun 12th Jan"
Added Mead on Twitter: "Here it is! So excited to announce that I’ll be working with my good friend @itreallyisjoe for the first time this Christmas 😊"