The planned drive in tour of Six The Musical has been cancelled completely.
The hit West End show was due to take to stages at 12 outdoor locations over the summer for a series of drive in shows.
However local lockdowns amid the ongoing pandemic have caused the cancellation of all planned performances.
Ticket holders will be contacted with refund options.
The tour formed part of Live Nation Entertainment's Utilita Live From The Drive-In.
The organisers said: "The latest developments regarding localised lockdowns mean it has become impossible for us to continue with the series with any confidence."
Six producers Kenny Wax, Wendy and Andy Barnes and George Stiles added in a statement: "This devastating news has come out of blue and hit us all for six. We are so sorry to disappoint the thousands of fans who have booked tickets and sold out many dates on the tour.
"It is also a sad day for our West End and UK Tour Queens who had already started rehearsals and our entire team of up to 60 people who were all working so hard to deliver a spectacular show.
"Despite the Government announcing stage three of Culture Secretary Oliver Dowden's road map permitting performances outdoors with an audience, the planned tour was due to visit 12 cities, several of which have since been identified as emerging Covid infection hot spots.
"We know that ultimately there is nothing more important than the safety and wellbeing of our company and the Six Queendom. We look forward to better times."
Picture: Josh Darvill for Stage Chat