Six The Musical is to play a socially distanced run at the Lyric Theatre in London's West End.
The show will move from The Arts Theatre to the new venue from November 14 through to January 31.
Six will play at the Lyric for a limited 11 week run with nine shows a week. Tickets are on sale now here.
Performances will take place following the latest guidelines including socially distancing and temperature checks.
The production will return to the Arts Theatre in 2021.
Together with the West End run, the show will also play at the Lowry in Salford for six weeks from November 27.
Producers Kenny Wax, Wendy and Andy Barnes and George Stiles said: "Across our two UK productions of Six we have the opportunity to give work to 100 or so actors, musicians, technicians, stage managers, production managers, costume makers, marketing, press, ticketing and office staff.
"We accept that with social distancing it is unlikely to be economically viable, but we hope to entertain many thousands of theatregoers who have been starved of live entertainment since March. We hope that opening Six will help build audience confidence and bring business back to the local economy.
"We also understand that restarting productions, particularly musicals, remains impossible for most producers for reasons of scale, finance and lack of cancellation insurance. We continue to look forward to the day when social distancing is removed and theatre can play to 100 per cent capacity."
The new production forms part of the reopening of Nimax's West End theatres with six London venues opening their doors for the first time since March.
Nominated for five Olivier Awards, SIX turns Tudor queens into pop princesses as 500 years of historical heartbreak becomes an hour of 21st century sass.
Six - written and composed by Toby Marlow and Lucy Moss - has become a huge hit since first premiering at the Edinburgh Fringe in 2017.
The musical has proved a global phenomenon with productions on Broadway in New York and Sydney, Australia alongside its ongoing run in London's West End and sold out UK tour.