The musical is based on the iconic music of American vocal group The Drifters.
Beverley Knight will play Faye Treadwell, manager of The Drifters who, together with her husband George Treadwell, turned the group into a global phenomenon.
Further casting is to be confirmed.
The production will include hit songs from The Drifters' back catalogue such as Save the Last Dance for Me, Under the Boardwalk, Kissin’ in the Back Row of the Movies, Stand by Me, Come on Over to My Place and Saturday Night at the Movies.
The Drifters Girl will premiere at the Theatre Royal Newcastle from 5 through to 19 September before transferring to London's West End at the Garrick Theatre from 1 October, currently booking through to 13 February.
The creative team will be led by director Jonathan Church with a book by Ed Curtis and design by Anthony Ward.
The show will feature choreography by Karen Bruce, lighting design by Ben Cracknell and music supervision and orchestrations by Chris Egan.